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Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences.This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.

toxicity --- anticoagulant activities --- Portunus pelagicus --- complement system --- Fucus distichus subsp. evanescens --- MytiLec-1 --- DNA methyltransferases --- malignant glioma --- heparin --- innate immunity --- polysialic acid (polySia) --- HddSBL --- differentiation induction --- phagocytosis --- fucosylated glycosaminoglycan --- Alzheimer’s disease --- thermostable --- amyloid-? --- lectins --- ?-secretase --- fucoidan --- oncolytic vaccinia virus --- Marinomonas --- viral replication --- BACE1 --- glioblastoma --- bioactivity --- Ehrlich ascites carcinoma --- adverse effects --- therapeutic effects --- ERK --- physicochemical characteristics --- oligo-fucoidan --- tandem duplication --- lectin --- galactooligosaccharides --- recombinant --- TTL --- theoretical model --- fucan sulfate --- retinal pigment epithelium --- glycosaminoglycan --- ?-galactosidase --- apoptosis-related genes --- C1q --- VEGF --- nanomedical devices --- epigenetic modification --- nematocyst discharge process --- Mytilus galloprovincialis --- pattern recognition receptors --- Pattalus mollis --- transglycosylation --- anti-viral --- nematogalectin --- heparan sulphate --- oxidative stress --- bivalve mollusks

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The last decade has seen many dramatic changes in cancer chemotherapy, with the introduction of a number of new forms of treatment as well as important developments in the more traditional fields of cytotoxic and hormonal therapy. Now in its second edition, this book summarizes the whole range of systemic cancer therapies and their clinical applications, taking into account new drugs and the emerging concept of personalized therapy. Intended as an introductory text for junior doctors, nurses and medical students, Cancer Chemotherapy in Clinical Practice is divided into three sections: ·         The Theoretical Basis of Cancer Chemotherapy – following a historical introduction the different treatment modalities are explained in the context of basic tumor biology ·         Practical Aspects of Chemotherapy – covering dosing and drug delivery together with an extensive discussion of possible side-effects and their management ·         Chemotherapy in the Management of Cancer – explaining the place of drug treatment and the outcomes that can be expected from chemotherapy in all the major cancers Written in a consistent style, this book makes a wealth of complex information both readily accessible and easily understandable.

Cancer -- Chemotherapy. --- Diseases --- Therapeutic Uses --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Neoplasms --- Antineoplastic Agents --- Medicine --- Health & Biological Sciences --- Oncology --- Anticancer Agents --- Antineoplastic Drugs --- Antineoplastics --- Antitumor Agents --- Antitumor Drugs --- Cancer Chemotherapy Agents --- Cancer Chemotherapy Drugs --- Chemotherapeutic Anticancer Agents --- Chemotherapeutic Anticancer Drug --- Agents, Anticancer --- Agents, Antineoplastic --- Agents, Antitumor --- Agents, Cancer Chemotherapy --- Agents, Chemotherapeutic Anticancer --- Chemotherapy Agents, Cancer --- Chemotherapy Drugs, Cancer --- Drug, Chemotherapeutic Anticancer --- Drugs, Antineoplastic --- Drugs, Antitumor --- Drugs, Cancer Chemotherapy --- Benign Neoplasms --- Malignancy --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Neoplasias --- Neoplasm, Benign --- Tumor --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Therapeutic Effects --- Effects, Therapeutic --- Uses, Therapeutic --- Pharmacy. --- Medicine. --- Cancer research. --- Oncology. --- Medicine & Public Health. --- Cancer Research. --- Oncology  . --- Chemistry --- Drugs --- Materia medica --- Pharmacology --- Cancer research

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Handy – concise – clear The "always on-hand" pocket guide to the treatment of infectious diseases. - The most important antibiotics and antimycotics: Spectrum – dosage – side-effects - Numerous tables sorted by substances, pathogens, indications - Administration of antibiotics during pregnancy, renal and hepatic insufficiency, dialysis - Including statements on the cost of therapy Numerous tips and troubleshooting guides: - Potential mistakes - Therapy failures - Perioperative antibiotic prophylaxis Adjusted to European standards: Up-to-date substances, authorizations, resistances and trade names. The first guide to antibiotic therapy for Europe! This book will most certainly be a valuable asset for all those treating patients with infections. While primarily aimed at the hospital setting, most of the very useful information can certainly be used in other healthcare settings, too. Andreas Voss Professor of Clinical Microbiology and Infection Control Radboud University Nijmegen Medical Centre and Canisius-Wilhelmina Hospital Nijmegen, The Netherlands.

Communicable diseases -- Handbooks, manuals, etc. --- Communicable Diseases -- handbooks. --- Infection -- Handbooks, manuals, etc. --- Medical microbiology -- Handbooks, manuals, etc. --- Anti-Bacterial Agents --- Anti-Infective Agents --- Therapeutic Uses --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Infectious Diseases --- Medicine --- Health & Biological Sciences --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Therapeutic Effects --- Effects, Therapeutic --- Uses, Therapeutic --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Microbicides --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agents --- Anti Microbial Agents --- Anti-Bacterial Compounds --- Anti-Mycobacterial Agents --- Antibacterial Agents --- Antibiotic --- Antimycobacterial Agents --- Bacteriocidal Agents --- Bacteriocides --- Antibiotics --- Agents, Anti-Bacterial --- Agents, Anti-Mycobacterial --- Agents, Antibacterial --- Agents, Antimycobacterial --- Agents, Bacteriocidal --- Anti Bacterial Agents --- Anti Bacterial Compounds --- Anti Mycobacterial Agents --- Compounds, Anti-Bacterial --- Medicine. --- Gynecology. --- Critical care medicine. --- Internal medicine. --- Infectious diseases. --- Otorhinolaryngology. --- Surgery. --- Medicine & Public Health. --- Infectious Diseases. --- Internal Medicine. --- Intensive / Critical Care Medicine. --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Surgery, Primitive --- Ear, nose, and throat diseases --- ENT diseases --- Otorhinolaryngology --- Medicine, Internal --- Intensive care --- Intensive medicine --- Emergency medicine --- Intensive care units --- Gynaecology --- Generative organs, Female --- Diseases --- Gynecology .

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Since the antibiotic inefficiency crisis leads to clinical and economical disabilities, one of the major challenges of scientists is to develop novel methods to handle infections. This book offers a perspective on alternate antimicrobial approaches based on naturally-derived products in order to modulate the virulence of pathogens and more

Anti-Bacterial Agents --- Virulence Factors --- Nanotechnology --- Bacterial Infections --- Natural Science Disciplines --- Toxins, Biological --- Anti-Infective Agents --- Bacterial Infections and Mycoses --- Miniaturization --- Technology --- Diseases --- Disciplines and Occupations --- Biological Factors --- Therapeutic Uses --- Chemicals and Drugs --- Technology, Industry, and Agriculture --- Pharmacologic Actions --- Chemical Actions and Uses --- Technology, Industry, Agriculture --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Therapeutic Effects --- Effects, Therapeutic --- Uses, Therapeutic --- Biologic Agents --- Biologic Factors --- Biological Factor --- Factor, Biologic --- Factor, Biological --- Factors, Biological --- Biological Agents --- Agents, Biologic --- Agents, Biological --- Biologic Factor --- Factors, Biologic --- Arts, Industrial --- Industrial Arts --- Miniaturisation --- Miniaturisations --- Miniaturizations --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Microbicides --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agents --- Anti Microbial Agents --- Biological Toxins --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Bacterial Infection --- Infection, Bacterial --- Infections, Bacterial --- Nanotechnologies --- Pathogenicity Factors --- Factors, Pathogenicity --- Factors, Virulence --- Anti-Bacterial Compounds --- Anti-Mycobacterial Agents --- Antibacterial Agents --- Antibiotic --- Antimycobacterial Agents --- Bacteriocidal Agents --- Bacteriocides --- Antibiotics --- Agents, Anti-Bacterial --- Agents, Anti-Mycobacterial --- Agents, Antibacterial --- Agents, Antimycobacterial --- Agents, Bacteriocidal --- Anti Bacterial Agents --- Anti Bacterial Compounds --- Anti Mycobacterial Agents --- Compounds, Anti-Bacterial --- Pharmacological and Toxicological Phenomena --- Drug Therapy --- Biological Products --- Cloud Computing --- Microchemistry --- Infection --- Parasites --- Toxoids --- Nanotubes --- Microchip Analytical Procedures --- Nanostructures --- Virulence --- Infections --- Anti-infective agents. --- Biotechnology. --- Microbiology. --- Infectious and parasitic diseases. --- Microbial biology --- Biology --- Microorganisms --- Molecular technology --- Nanoscale technology --- High technology --- Chemical engineering --- Genetic engineering --- Antiinfective agents --- Antimicrobial agents --- Antimicrobial drugs --- Antimicrobials --- Drugs --- antimicrobial therapy, molecular modulation, virulence, drug delivery nanoshuttles.

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Antihypertensive Agents --- Hypertension --- Hypertension. --- Life Style. --- therapeutic use. --- complications. --- physiopathology. --- therapy. --- Vascular Diseases --- Psychology, Social --- Cardiovascular Agents --- Life Style --- Cardiovascular Diseases --- Therapeutic Uses --- Behavior and Behavior Mechanisms --- Diseases --- Psychiatry and Psychology --- Pharmacologic Actions --- Chemical Actions and Uses --- Chemicals and Drugs --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Pharmacological and Toxicological Phenomena --- Drug Therapy --- Behavior And Behavior Mechanism --- Therapeutic Effects --- Therapeutic Effect --- Therapeutic Use --- Effect, Therapeutic --- Effects, Therapeutic --- Use, Therapeutic --- Uses, Therapeutic --- Cardiovascular Disease --- Disease, Cardiovascular --- Diseases, Cardiovascular --- Cardiology --- Anti-Hypertensive Agents --- Anti-Hypertensive Drugs --- Anti-Hypertensives --- Antihypertensive Drugs --- Antihypertensives --- Anti-Hypertensive --- Anti-Hypertensive Agent --- Anti-Hypertensive Drug --- Antihypertensive --- Antihypertensive Agent --- Antihypertensive Drug --- Agent, Anti-Hypertensive --- Agent, Antihypertensive --- Agents, Anti-Hypertensive --- Agents, Antihypertensive --- Anti Hypertensive --- Anti Hypertensive Agent --- Anti Hypertensive Agents --- Anti Hypertensive Drug --- Anti Hypertensive Drugs --- Anti Hypertensives --- Drug, Anti-Hypertensive --- Drug, Antihypertensive --- Drugs, Anti-Hypertensive --- Drugs, Antihypertensive --- Calcium Channel Blockers --- Life Style Induced Illness --- Lifestyle --- Lifestyle Factors --- Factor, Lifestyle --- Life Styles --- Lifestyle Factor --- Lifestyles --- Quality of Life --- Social Environment --- Blood Pressure, High --- Blood Pressures, High --- High Blood Pressure --- High Blood Pressures --- Blood Pressure --- Cardioactive Agents --- Cardioactive Drugs --- Cardiovascular Drugs --- Cardioactive Agent --- Cardioactive Drug --- Cardiovascular Agent --- Cardiovascular Drug --- Agent, Cardioactive --- Agent, Cardiovascular --- Agents, Cardioactive --- Agents, Cardiovascular --- Drug, Cardioactive --- Drug, Cardiovascular --- Drugs, Cardioactive --- Drugs, Cardiovascular --- Sympathomimetics --- Psychology, Perceptual --- Social Psychology --- Perceptual Psychology --- Disease, Vascular --- Diseases, Vascular --- Vascular Disease --- Adverse Cardiac Event --- Cardiac Events --- Major Adverse Cardiac Events --- Adverse Cardiac Events --- Cardiac Event --- Cardiac Event, Adverse --- Cardiac Events, Adverse --- Event, Cardiac